SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '70299478dbe9bb8063fb65a278233cacb9e2ec07ed4a9c165d81fe84ba64dccc' 
  AND token = 'wWt4Po0wRoMHKQx1M7sVXT3iFBQfsRdwJyhvJWhJEwI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}