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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c03f4478a7a87b35fa6160be1e8c17836d14d28f60a003ad7f11e6b57b109bd' 
  AND token = '53p4LbiG5gW5S/CB5C1zWkmnWIndxA4IDLDSp4KKlb4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}