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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bea27c500c55b29a5fb94ec875305463dc76dea654067acf446035186c102876' 
  AND token = '1uO9jy7tiALP7KDU6UZ5a/AVbG7V4UOGZOrHx5fvDDE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}