SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c75f3e2a80f6cf0984bb9ef36f6f1c8237d15dabc135365768e446ebf429bc63' 
  AND token = '7yWr0Kzlq0GxcKJcs/Ylx6DKEVkl5SMmugQC8xJKdE8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}