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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec4b6d04e88b293ec9ce3a1f9f1ea694cf842bc966d017597332f055775eec5d' 
  AND token = 'j9FLcMkETHLdhWzVFy13bYkpe5ijeCtyZN5HEjIf924=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}