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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18ea0e0cb3c0753934a0429360c5b50e329ca71b9803d003f894d8b95538a461' 
  AND token = 'TQc0NG6ofSgGrPm+1uXMJ9S7FPkkRn5s4z5zyB34f1E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}