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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b5fccabaf58f125090cd4d5470ef42140be53ea8d16c49e78e36da40caf347a' 
  AND token = 'j1LlStle3pq8v/8p7LDdx8B9AtWmTbMEvixH+OefkFI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}