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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '048f12b0f56f7cf296f0c3770bf9d8a1b8d3810de4f8f5cfdd881d59ee257126' 
  AND token = '/BG1cY8bdwaLmIaRGkKSPiNnDYhoa1Ym9VywRIE8FzQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}