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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e40735fa300f13cd8ecfdcec92aa726bba2ca98536318242308815eb38b890b' 
  AND token = 'jHPz98B3JCXnBSXYyb04zZhiZg4kvmB+sZMce57EYFc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}