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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea86c7c5bd1c802c570bda78302f7850ae91e6cf7254ee50a68f3444acf83bae' 
  AND token = 't+GlNZly022AsXAUWnGNbabmFytTgORD8TyI6HIGGZc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}