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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bf95bbd69abb4d3d2f8b4a061f0224a72219c17a6ccdbfea16ac77210c9601d5' 
  AND token = '4/0HKBcVWD5NxPVMl2BXSjtRDUSqJ8Jhr2DE66HwT98=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}