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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f88f458e64c8bb455b4c0f46b019da8adb7b6492a25d1c848ec3705e4114639a' 
  AND token = 'ZpK4CkIPbYjX+ZnOWDeT5120ksTF7qOtkQQwPT0WJ8o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}