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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74e558afdffcf1fd5767c53d799393fc8f5d9c751f2e3d394d8c70903b69ea1b' 
  AND token = 'FkLPoFgSAM0j5mJ989YuOQDw742GuXAtAZ31GnTBwKQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}