SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef8e3d5629c2fbc13037843d68f673a200fcda8d5d92f247eed9a0ee9c7b0752' 
  AND token = 'iq64ZJrbEDyIH6fD7VWXn/CKu0/jmnJZQxalOYc8HyY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}