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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2fc740eb646cbf6ef65f9dcce453c27583150ea1cd4a16fed7c7eebd79369f62' 
  AND token = 'IrVUX/FXG5Kv1RACMCgc4QETaN3x3s+XV/y+UxeabOI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}