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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e81c6abd23e54b96bc4e469983fbc115a2a2cc55f4da1502f0a9f0bfc90816d' 
  AND token = 'jWwrk4oYqMi76PD9b8mKowTpGZgHOc2xW4ZAt03PSM0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}