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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46aa407a791f82572f38e28283e28609c749cd43dadb1d6cfad1fea7ba1cb5b4' 
  AND token = 'si2HnBZY7sXWVFWaLeJRZTcSyFcwkJMFPI55UROFxZA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}