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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'db06acac4c62b41af9e56cbafb7fb94649e06961144ee747d80e4e9b39b28948' 
  AND token = 'gy1ZBe73dmxF8kaPyRjTW4dwcBqcqNjDXZ0rwIyzrUA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}