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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '61170bb0bccac8231618b7cf2b8404e2dc19a413a2a05aceec5ed2b782193500' 
  AND token = 'BqzALv/vILZUs44WRhPdFrhKpQNH3KK0Cnr/ISWMyvQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}