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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef24842e03fdd0ca5a5a6cf97e1162c0db4514dcc2e69cce36c83cb27366db5d' 
  AND token = 'qC5K6Pl2sqNfwd4LtB+kBglvVmAKNfQmLRL+b9GVjOo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}