SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c3fa37eae90585957843404c495066dc0fbfa788c229af7a6d77b5146504e9b3' 
  AND token = 'QP7BZ7qEAMsv28L2odqhP7/R3KRzQvi2DrddNtXZtx8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}