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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75a7f70c1822ab02a20288a1525d4f27f250cf9875ad07f35176759ba80d60a4' 
  AND token = 'Y5PZlJ58Cq0f9uf05VVrz9bUQW/Rg24vdqcDAwnhHBk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}