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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a7b9811c050e72302d40df7fa605e5b783d43c71b0c0fff089c90ca9c8124c4' 
  AND token = '2IRm0TVsMVe1eC++Y5wgkZfRs22Mn98mAW1wZmXwFmw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}