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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a9f53e6bf3bb60a977d3e2167864730312deb411b72a5706e06226fe921fb265' 
  AND token = 'Y3QocuWa/1tLNN+0jGqUJ0VWViS7E2BiDW3lA7UoiHI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}