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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '85432433a76603c1887d52182cf56f8af313419234a2e011dbd2a225d1b1fb9e' 
  AND token = 'uJ0g8Jwwn7qczrYGrkNiCW8ysl7L2+Y04tUgGgwerSI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}