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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '11a6c6c6e22742f53eb7ab8db3857db35f389b1de1c71ce1bb187f736abedb09' 
  AND token = '1t6gaDa3i/jnCF2TagwP9z5X1ONQ+1HC7av3ES4hxmA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}