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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4557a5854a6bbf31a45256a218ffbfc53c6e347e71c17a1d1b051cc63c625824' 
  AND token = 'J9NcsbtzsXXy+tL0I/jDfY0yfWybzZ3NVQ/NN5a1vXM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}