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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43190bd27ac76307b321843bf96f5aac0a5af1ec5e859ce331bc3f38410fd378' 
  AND token = '8T9tmnaxzi/URsTCDz2DTc73jX4ysIF7bHVb8lN8rWc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}