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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5d927ff517a4e58f9b3890ace10b7580e69fc4686ac3fec8e7f68f2f29cbc22' 
  AND token = '/7+vz7Ll7xGK8sV5TgVsvuZkMkre9g5vVxVwSM23RfM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}