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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52ccf62240b13d70e23b22e5d506f1580df830278d352dd70ff6e6eb61770d0e' 
  AND token = '7iUXlaoDT+SiDCgd9rSlqGlQmxIt0Evb5+W4SQqpUs8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}