SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '545f9c90e712d32130c5e6b29fc5df26b9a330e086459c2c79c994fa89285225' 
  AND token = 'qw440RfQpg+wkpuVOuQc5olsKLzhu/qvWuB0J9VCMVQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}