SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2bdc3f075897fe42f74e4e84c282403ff28448cd8418a2ad1208b11b57359e6f' 
  AND token = 'hOFRns+ZTfX920TOXrOn/pIEvCQcRyDxbOB5hLY4L0U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}