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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '55dd59b2bac77e12e08ce747ec80be1a08aa50b8cca3f46b7ae941f9689de448' 
  AND token = 'sZ2dqd7VaEh/hDPDeeVwS+9Mky+k1U4HNMx6gVMNFpo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}