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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f8bdd0c32b7344b7ed57f28185d4219015d8145277fc4f4b206dbfd6321b1037' 
  AND token = 'WmNL5/MVhCPGT7EZt2IVxbmN+JZK0kkR8loRH8EbY2Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}