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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '811ef0bc084f7608169ecfdd400d36997e9a57f67bf923a73cdd1c36bbb0fc35' 
  AND token = 'QSm0PWK+iyvq9qEdbo9hYC09ijSDZSWZOgAit5+y+mA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}