SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ce8ceab1d5855705fb6315cfd327c2435d04dfbe217c9e5aca49b8819d746e6' 
  AND token = '9Mh4yI5l8Ad+F5u6JItzcxjdNR2Lnlukf4sKPcYDfLE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}