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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ab7de5601708b8bd21f2683e25f62657e1ea4c15d74adf1ca7fa22b15e77e7cf' 
  AND token = 'F7+zZkQEPvERQrZYo+yloBThDmVPk749NR1SvMwO+OM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}