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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b72cb61e1e2efae73b5bb4e636bd3b36ef1bbefc8f6e365d055ad3b4aec2373d' 
  AND token = 'GKwXr30DmYIFIjYLNF9Jweet4BVXeS+qC6vwMvXD3qs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}