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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c8a89a6d847dd940085c25f1c279152c6fb0ba55e721544d81a5f32da84affc' 
  AND token = '+SeicSDK0MzzMwCP+i/PFDeSPulQznIhw2tAC1YVXso=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}