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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2be6a862da7c21003344a3b0213afb276c1da74734e70b03e574f43d3aa7751' 
  AND token = 'z/VWr3O7Hy65h+D3CSCt0K/rsq0GAKbXVZANV8HmVj0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}