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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2818b255aba98d117abf8921c76a69c471542a428fc53f180c014a35226cdc74' 
  AND token = 'R+9Tn7TbVERWzN3tp/75nRF07SI8/Xqya7ecmS+Z70k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}