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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b2f4228a738f9638087f34d58a0c8d535e535b539f6993d3d842f11ba5ec539e' 
  AND token = '0g/UBXYK524gQ98Mn4PDW9uGuKvXIVw29ko6rZEAWM0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}