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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5d822459485dd8bb8be348f9e5731a1a1e549d6eb83621e3043e0f7b2be3f5a' 
  AND token = 'rS55wpwDreHwCc5ae9LDalit/RRXNAHnUqaZjaci2IE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}