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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9318157e33b3a56a501e830ec3a5076dd614b482249f6b92017c94640eb1277c' 
  AND token = 'bki6U/jeMYvtJVydAqyMsWvGsLT8qSFW2a+qvaHfQAc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}