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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '175001d867a65fb70a4dad5dda629f4df27251735897a59b072bdfd3a5f48629' 
  AND token = 'S8+hoSFoc+vWJa74CRjI5FQGAtBG4fDnRTlAc5vildE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}