SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bf25d1675e172f32f6348c043c685a071e5c04bd54b5ca1ef146d5183810e6ba' 
  AND token = 'OzRI7SUa3lBYjIRCJbkSN5tuLp2AVGaZ6OagTtB83Yg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}