SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9aa67b6eaa92cc118bcf204e250ecb3b73c40adc2e8808a20366c486750e012a' 
  AND token = 'EtqYvGtWUoV/kzws/YXHklx4jUt216D5oCrfyZUCFx0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}