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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '677a9f001307c53ea6a847a47e2a6c6a2ac94d60bbd562fe63f5c0a24fc9e670' 
  AND token = 'Y/Lfwfka7dE5Do6jp3Km21SlwxjNvjP0MCCnLGgQFP4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}