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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '08d78d24078632ffe14704d80d0d46d84e5f983976cba0bf0c59c2408ec5e757' 
  AND token = 'qvFFA6P4nxsLSJg2VxmuITch2xIwfui9PcumFfHcFJ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}