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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6e65c29e61a318fa076c16c2127cb692bb4f6b6218f095686820955ab34ca16' 
  AND token = 'A8Zy2mPRIERWyQeyda6eOA5GOVLFf1znInWXACdKEiQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}